There's a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors from the dorsal horn to lessen afferent suffering transmission and develop analgesia. Thus, medicine like clonidine that target alpha-2 receptors can affect the transmission of pain. Jun 10, 2024 · If clonidine therapy should https://www.proleviate.com/post/the-new-pain-killer-conolidine